Table 3.
Multivariate logistic regression analysis of variables related to LNM.
| Variables | OR | 95% CI | p value |
|---|---|---|---|
| Age at diagnosis | |||
| ≥65 | Reference | ||
| 50–65 | 1.354 | 0.931–1.970 | 0.113 |
| <50 | 1.248 | 1.080–1.442 | 0.003 |
|
| |||
| Race | |||
| White | Reference | ||
| Black | 1.064 | 0.886–1.277 | 0.510 |
| Other | 1.538 | 1.109–2.133 | 0.010 |
|
| |||
| Sex | |||
| Male | Reference | ||
| Female | 0.939 | 0.784–1.123 | 0.489 |
|
| |||
| Primary site | |||
| Supraglottis | Reference | ||
| Glottis | 0.289 | 0.252–0.354 | <0.001 |
| Subglottis | 0.254 | 0.169–0.381 | <0.001 |
| Larynx | 0.522 | 0.408–0.669 | <0.001 |
| Other | 0.511 | 0.390–0.670 | <0.001 |
|
| |||
| Number of tumours | |||
| 1 | Reference | ||
| >1 | 0.744 | 0.642–0.863 | <0.001 |
|
| |||
| Tumour size | |||
| ≤3 cm | Reference | ||
| >3 cm | 1.742 | 1.498–2.026 | <0.001 |
|
| |||
| Grade | |||
| Grade I | Reference | ||
| Grade II | 2.438 | 1.818–3.267 | <0.001 |
| Grade III and IV | 4.609 | 3.407–6.235 | <0.001 |
|
| |||
| T-stage | |||
| T1 | Reference | ||
| T2 | 2.923 | 2.231–3.829 | <0.001 |
| T3 | 3.925 | 3.030–5.084 | <0.001 |
| T4 | 5.890 | 4.571–7.590 | <0.001 |
Notes: p < 0.05 represents a statistically significant difference. Abbreviations: LNM, lymph node metastasis.