Table 2.
Characteristics of the sample grouped as high risk (FRAX ≥ 20) or low risk (FRAX < 20)
| FRAX | ||||||||
|---|---|---|---|---|---|---|---|---|
| < 20 | ≥ 20 | |||||||
| Characteristics | All | Treated | Untreated | p value | All | Treated | Untreated | p value |
| (n = 708) | (n = 406) | (n = 302) | (n = 148) | (n = 122) | (n = 26) | |||
| Age [years] | 61.7 ± 8.9 | 62.6 ± 8.6 | 60.4 ± 9.1 | < 0.001 | 73.4 ± 8.7 | 73.6 ± 8.5 | 72.4 ± 9.8 |
0.41 0.23 0.51 0.86 |
| BMI [kg/m2] | 23.8 ± 4.0 | 23.6 ± 3.9 | 23.8 ± 4.3 | 0.58 | 24.4 ± 4.0 | 24.4 ± 4.1 | 24.1 ± 3.6 | |
| Familiarity [%] | 31.9 | 30.3 | 34.1 | 0.62 | 43.2 | 41.0 | 53.8 | |
| Age at menopause [years] | 49.2 ± 4.7 | 49.1 ± 4.9 | 49.4 ± 4.6 | 0.47 | 49.2 ± 5.7 | 49.2 ± 5.8 | 49.2 ± 5.5 | |
| Type of menopause [%] | ||||||||
| Early menopause | 16.9 | 17.8 | 15.6 |
0.87 0.025 0.96 0.25 |
17.0 | 15.7 | 23.1 | 0.74 |
| Physiological menopause | 82.0 | 79.1 | 86.0 | 77.0 | 77.3 | 76.0 | 0.86 | |
| Surgery menopause | 14.8 | 16.3 | 12.8 | 20.0 | 20.0 | 20.0 | 0.52 | |
| Pharmacological menopause | 3.3 | 4.7 | 1.5 | 3.0 | 2.7 | 4.0 | 0.39 | |
| Breastfeeding [months] | 8.9 ± 9.9 | 8.9 ± 10.1 | 8.8 ± 9.5 | 0.36 | 12.7 ± 14.6 | 12.9 ± 15.3 | 11.3 ± 10.4 | 0.89 |
| Current smoking habits [%] | 8.6 | 9.4 | 7.6 | 0.58 | 6.1 | 4.9 | 11.5 | 0.41 |
| Previous smoking habits [%] | 18.6 | 17.7 | 19.9 | 0.96 | 17.6 | 13.1 | 38.5 | 0.002 |
| Years smoking | 23.6 ± 13.8 | 24.0 ± 13.9 | 23.1 ± 13.7 | 0.63 | 31.5 ± 15.5 | 33.6 ± 17.3 | 27.2 ± 10.6 | 0.52 |
| Susceptibility to falling [%] | 5.6 | 5.9 | 5.3 | 0.54 | 16.2 | 17.2 | 11.5 | 0.11 |
| Diabetes [%] | 2.8 | 2.5 | 3.3 | 0.53 | 8.1 | 7.4 | 11.5 | 0.24 |
| Drugs [%] | ||||||||
| Cortisone | 8.1 | 10.3 | 5.0 | 0.009 | 23.0 | 20.5 | 34.5 | 0.74 |
| Aromatase inhibitors | 0.8 | 0.5 | 1.3 | 0.87 | 0.0 | 0.0 | 0.0 | 0.15 |
| Anticoagulants | 1.4 | 0.7 | 2.3 | 0.89 | 3.4 | 3.3 | 3.8 | 0.13 |
| DEXA T score | ||||||||
| Lumbar spine | − 2.4 ± 1.0 | − 2.7 ± 1.0 | − 2.1 ± 1.0 | < 0.001 | − 2.7 ± 1.3 | − 2.8 ± 1.2 | − 1.9 ± 1.4 | < 0.001 |
| Total hip | − 1.6 ± 0.8 | − 1.7 ± 0.8 | − 1.4 ± 0.8 | < 0.001 | − 2.4 ± 0.8 | − 2.4 ± 0.8 | − 2.1 ± 0.7 | 0.12 |
| Vertebral fractures [%] | 24.2 | 33.5 | 11.6 | < 0.001 | 75.7 | 83.6 | 38.5 | < 0.001 |
| Femur fractures [%] | 1.8 | 2.7 | 0.7 | 0.045 | 10.1 | 9.0 | 15.4 | 0.23 |
| FRAX | ||||||||
| Major fractures | 9.3 ± 4.4 | 10.3 ± 4.4 | 7.9 ± 4.1 | < 0.001 | 30.0 ± 11.1 | 30.4 ± 11.0 | 27.8 ± 11.2 | 0.25 |
Statistically significant p values are in italics
Numbers are means ± SD, medians (interquartile range), or counts (%), as appropriate