Table 2.

Univariate and multivariate logistic regression analysis of factors associated with the achievement of remission (DAS28 < 2.6) in patients with RA.

	Univariate		Multivariate†
	OR	95% CI	OR	95% CI
Age	0.99	0.96–1.02
Disease duration (year)	0.90	0.79–1.00
BMI	1.09	0.96–1.24
Baseline erosions of hands or feet	0.54	0.18–1.42
Baseline JSN of hands or feet	0.42	0.15–1.05
Baseline PtGA (0–100)	0.98*	0.96–0.99	0.99	0.97–1.02
Baseline PhGA (0–100)	0.98	0.96–1.00
Baseline Td joint (yes)	0.68	0.23–2.62
Baseline swollen joint (yes)	0.49	0.18–1.33
Baseline DAS28	0.49***	0.31–0.71	0.56*	0.35–0.88
Baseline HAQ	0.31**	0.13–0.66	0.57	0.21–1.39
Smoking
Nonsmoker	(reference)
Ex-smoker	1.30	0.17–7.05
Current smoker	0.77	0.13–5.46
Regular exercise (yes)	1.35	0.58–3.13
Rheumatoid factor positive	1.61	0.53–6.04
ACPA positive	1.13	0.45–3.03
Baseline ESR (mm/h)	0.95***	0.93–0.98
Baseline CRP (mg/dL)	0.77*	0.12–0.74
Previous bDMARDs use	0.42	0.06–1.69
Methotrexate	2.04	0.61–9.36
Glucocorticoid dose (mg/day, equivalent to prednisolone)	1.03	0.85–1.25
NSAID	0.66	0.14–2.30
Female	0.51	0.15–1.86

OR odds ratio, CI confidence interval, RA rheumatoid arthritis, BMI body mass index, JSN joint space narrowing, NSAID nonsteroidal anti-inflammatory drug, bDMARDs biological disease-modifying antirheumatic drugs, TNFi tumor necrosis factor inhibitor, CRP C-reactive protein, ESR erythrocyte sedimentation rate, RF rheumatoid factor, ACPA anticitrullinated protein antibody, PhGA physician’s global assessment, PtGA patient’s global assessment, DAS28 disease activity score 28, HAQ health assessment questionnaire.

^†All variables with p-values < 0.05 in univariate logistic regression analyses were included in multivariate analysis, except for variables with variance inflation factor > 10.

*p < 0.05, **p < 0.01, ***p < 0.001.