. 2022 Nov 19;12:19957. doi: 10.1038/s41598-022-24466-1

Table 3.

Mortality rates and multivariable Cox regression of all-cause mortality in cancer patients with preexisting DM.

	Subjects (n)	Events (n)	Person-years	Mortality Rate	Model 1 (95% CI)	Model 2 (95% CI)
None	1,271	305	6,889	442.75	1 (Reference)	1 (Reference)	1 (Reference)	0.15	1 (Reference)	1 (Reference)	1 (Reference)	0.37
DKD	1,113	444	4,734	937.96	2.02 (1.75, 2.34)	1.85 (1.56, 2.18)	2.42 (1.79, 3.28)		1.55 (1.33, 1.81)	1.51 (1.27, 1.8)	1.7 (1.22, 2.37)

Subjects (n)

Events (n)

Person-years

Mortality
Rate

Model 1 (95% CI)

Model 2 (95% CI)

Overall

Male

Female

P for interaction

Overall

Male

Female

P for interaction

None

1,271

305

6,889

442.75

1 (Reference)

0.15

1 (Reference)

0.37

DKD

1,113

444

4,734

937.96

2.02

(1.75, 2.34)

1.85

(1.56, 2.18)

2.42

(1.79, 3.28)

1.55

(1.33, 1.81)

1.51

(1.27, 1.8)

1.7

(1.22, 2.37)

*Abbreviations: BMI Body Mass Index, DM Diabetes Mellitus, DKD Diabetic Kidney Disease.

*Mortality rate was calculated by dividing death cases by 10,000 person-years.

*Model 1 is the unadjusted model; Model 2 is adjusted for age, sex, BMI, smoking status, alcohol consumption, history of hypertension, and cancer types.

*P for interaction was tested by two-way interaction.