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. 2022 Nov 19;12:19917. doi: 10.1038/s41598-022-24089-6

Table 2.

Effect of different amounts of catalysts, temperature and solvent (5 mL) in the triazole-dihydropyrano[3,2-b]pyran.

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Entry Solvent Conditions Catalyst (mg) Time (h) Yield (%)
1 H2O r.t. 10 4 10
2 t-BuOH r.t. 10 6 Trace
3 DMF r.t. 10 6 25
4 MeOH r.t. 10 4 65
5 t-BuOH: H2O (2:1) r.t. 10 6 45
6 H2O r.t., US 10 2 80
7 MeOH r.t., US 10 2.5 70
8 t-BuOH r.t., US 10 3 35
9 DMF r.t., US 10 1.5 50
10 H2O 60, US 10 1 93
11 H2O 80, US 10 1 93
12 H2O 60, US 5 1.5 75
13 H2O 60, US 15 1.5 93

Significant values are in bold.