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Study outcomes. (a) Survival by group (daily LHF-535 administration initiated 24 h post-infection (PI) for group 2 and 72 h PI for group 3); (b) Average body weight; and (c) Average body temperature. Body temperature recorded in one group 3 animal was consistently 2.5 °C lower than the other animals in the group and was excluded from the averages shown here; had it been included, average group 3 temperatures would be 0.3 °C lower.
