Table 2.

Relationship between pathological characteristics of non-squamous non-small cell lung cancer patients and Beclin 1 expression, EGFR and ALK mutations

Characteristics		High Beclin 1	P	EGFR+	P	ALK+	P
No. patients	480	235		233		75
Age (years), n			0.750		0.650		0.550
≥ 70	254	123		126		45
60–69	226	112		107		30
Gender, n			0.218		0.246		0.234
Male	265	124		125		44
Female	215	111		108		31
Smoking, n			0.296		0.117		0.423
Yes	145	123		98		32
No	335	117		135		43
Lymph node metastasis, n			0.009		0.010		0.010
Yes	321	155		68		9
No	159	80		165		66
TNM stage, n			0.050		0.015		0.013
I–II	231	22		155		70
III–IV	249	213		78		5
Tumor differentiation, n			0.009		0.032		0.043
Low-grade	112	22		144		40
Intermediate-grade	167	44		56		23
High-grade	201	169		33		12
Prognosis, n			0.019		0.015		0.011
Survival	345	156		198		67
Death	135	79		35		8