Table 1.
Case | Age (years) | Clinical presentation | Surgical procedure | Tumor site and size | Serous component | Mesonephric component | Extraovarian disease |
---|---|---|---|---|---|---|---|
1 This study | 70 | Liver lesion and carcinomatosis | TH-BSO, omentectomy | Right ovary: 6.2 cm; left ovary: 2.9 cm | Right ovary: SBT/LGSC; left ovary: SBT | MLA | Liver metastasis; omental metastasis with mixed MLA (95%) and invasive LGSC (5%) |
2 This study | 58 | Bilateral ovarian masses | TH-BSO, omentectomy, staging biopsy | Left ovary: 30cm; right ovary: 17 cm | Bilateral SBT | Mesonephric-like differentiation/hyperplasia | Non-invasive implants |
3 Chapel et al. [16] | 80 | 2 months of abdominal pain | TH-BSO, omentectomy and tumor debulking after neoadjuvant chemotherapy | Right ovary: 10.6 cm | SBT and invasive LGSC | MLA | Metastatic MLA: sigmoid mesentery, rectosigmoid serosa and splenic omentum; Mixed MLA (major) and LGSC (minor): uterine serosa and right pelvic sidewall, and in additional metastatic foci on the omentum and rectosigmoid serosa and epiploica |
4 McCluggage et al. [15] | 61 | Pelvic pain and vaginal discharge | TH-BSO, omentectomy, resection of peritoneum from the Pouch of Douglas, and bilateral pelvic lymphadenectomy | Left ovary: 6 cm; Right ovary: 3 cm | Bilateral SBT | MLA | Invasive LGSC (invasive implants) in the Pouch of Douglas and 1 pelvic lymph node |
5 Dundr et al. [17] | 61 | Advanced tumor of the left ovary with abdominal spread and liver metastases | TH-BSO, omentectomy, portion of liver, diaphragm, appendectomy, a resection of an umbilical metastasis | Left ovary: 3.5 cm | SBT | MLA | Omentum and liver with metastatic MLA |
6 da Silva et al. [7] | 66 | - | - | Ovary: 5.4 cm | SBT | MLA | Left rectal mesentery (both components) |
7 da Silva et al. [7] | 62 | - | - | Bowel (metastasis): 7.5 cm | Invasive LGSC | MLA | Bowel (both components) |
8 da Silva et al. [7] | 61 | - | - | Ovary: 4.1 cm | SBT/LGSC | MLA | Peritoneal and omental carcinomatosis (both components), lung, bowel, liver, abdominal and intrathoracic lymph nodes |
9 d'Amati et al. [18] | 74 | Abdominal discomfort; RSO for an ovarian serous cystadenoma at age of 27 | TH-LSO, omentectomy, large-bowel segmental resection, and resection of two peritoneal nodules | Left ovary: 4.5 cm | SBT and invasive LGSC | Mesonephric-like carcinosarcoma | Metastatic MLA: omental and peritoneal nodules; carcinosarcoma: large bowel serosa nodule |
BSO: bilateral salpingo-oophorectomy; LGSC: low-grade serous carcinoma; LSO: left salpingo-oophorectomy; MLA: mesonephric-like adenocarcinoma; RSO: right salpingo-oophorectomy; SBT: serous borderline tumor; TH: total hysterectomy
IHC: immunohistochemistry; LGSC: low-grade serous carcinoma; SBT: serous borderline tumor