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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Int J Gynecol Pathol. 2022 May 20;42(2):182–191. doi: 10.1097/PGP.0000000000000868

Table 1.

Clinicopathological features in the current and published cases of ovarian combined SBT/LGSC and mesonephric-like lesion

Case Age (years) Clinical presentation Surgical procedure Tumor site and size Serous component Mesonephric component Extraovarian disease
1 This study 70 Liver lesion and carcinomatosis TH-BSO, omentectomy Right ovary: 6.2 cm; left ovary: 2.9 cm Right ovary: SBT/LGSC; left ovary: SBT MLA Liver metastasis; omental metastasis with mixed MLA (95%) and invasive LGSC (5%)
2 This study 58 Bilateral ovarian masses TH-BSO, omentectomy, staging biopsy Left ovary: 30cm; right ovary: 17 cm Bilateral SBT Mesonephric-like differentiation/hyperplasia Non-invasive implants
3 Chapel et al. [16] 80 2 months of abdominal pain TH-BSO, omentectomy and tumor debulking after neoadjuvant chemotherapy Right ovary: 10.6 cm SBT and invasive LGSC MLA Metastatic MLA: sigmoid mesentery, rectosigmoid serosa and splenic omentum; Mixed MLA (major) and LGSC (minor): uterine serosa and right pelvic sidewall, and in additional metastatic foci on the omentum and rectosigmoid serosa and epiploica
4 McCluggage et al. [15] 61 Pelvic pain and vaginal discharge TH-BSO, omentectomy, resection of peritoneum from the Pouch of Douglas, and bilateral pelvic lymphadenectomy Left ovary: 6 cm; Right ovary: 3 cm Bilateral SBT MLA Invasive LGSC (invasive implants) in the Pouch of Douglas and 1 pelvic lymph node
5 Dundr et al. [17] 61 Advanced tumor of the left ovary with abdominal spread and liver metastases TH-BSO, omentectomy, portion of liver, diaphragm, appendectomy, a resection of an umbilical metastasis Left ovary: 3.5 cm SBT MLA Omentum and liver with metastatic MLA
6 da Silva et al. [7] 66 - - Ovary: 5.4 cm SBT MLA Left rectal mesentery (both components)
7 da Silva et al. [7] 62 - - Bowel (metastasis): 7.5 cm Invasive LGSC MLA Bowel (both components)
8 da Silva et al. [7] 61 - - Ovary: 4.1 cm SBT/LGSC MLA Peritoneal and omental carcinomatosis (both components), lung, bowel, liver, abdominal and intrathoracic lymph nodes
9 d'Amati et al. [18] 74 Abdominal discomfort; RSO for an ovarian serous cystadenoma at age of 27 TH-LSO, omentectomy, large-bowel segmental resection, and resection of two peritoneal nodules Left ovary: 4.5 cm SBT and invasive LGSC Mesonephric-like carcinosarcoma Metastatic MLA: omental and peritoneal nodules; carcinosarcoma: large bowel serosa nodule

BSO: bilateral salpingo-oophorectomy; LGSC: low-grade serous carcinoma; LSO: left salpingo-oophorectomy; MLA: mesonephric-like adenocarcinoma; RSO: right salpingo-oophorectomy; SBT: serous borderline tumor; TH: total hysterectomy

IHC: immunohistochemistry; LGSC: low-grade serous carcinoma; SBT: serous borderline tumor