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ADME properties of the natural photosensitizer.
| Properties | Propolis-benzofuran A |
|---|---|
| GI absorption | High |
| BBB permeant | No |
| P-gp substrate | Yes |
| CYP2C19 inhibitor | No |
| CYP2C9 inhibitor | Yes |
| CYP2D6 inhibitor | No |
| CYP3A4 inhibitor | Yes |
| Skin Permeation Value (log Kp) cm/s | −6.51 |
Abbreviations: GI, gastro-intestinal; BBB, blood brain barrier; P-gp, P-glycoprotein; CYP, cytochrome-P.
