Table 1.
Variables | Deceased patients (n = 1149) | Recovered patients (n = 1342) | P-value |
---|---|---|---|
Mean age ± SD | 59.3 ± 10.9 | 51.0 ± 13.0 | < 0.001* |
Gender (male/female) | 611/538 (53.2/46.8%) | 697/645 (51.9/48.1%) | 0.537 |
ALT, IU/L (mean ± SD) (Reference range: 5–40) | 44.5 ± 23.9 | 33.2 ± 24.3 | < 0.001* |
AST, IU/L (mean ± SD) (Reference range: 5–40) | 36.9 ± 13.0 | 31.3 ± 15.7 | < 0.001* |
ALP, IU/L (mean ± SD) (Reference range: up to 306) | 201.9 ± 66.3 | 171.0 ± 90.6 | < 0.001* |
Cholesterol, mg/dL (mean ± SD) (Reference range: 50–200) | 116.6 ± 38.9 | 121.8 ± 36.3 | < 0.001* |
TG, mg/dL (mean ± SD) (Reference range: 60–165) | 116.6 ± 41.7 | 131.5 ± 61.5 | < 0.001* |
LDL, mg/dL (mean ± SD) (Reference range: up to 150) | 70.2 ± 35.6 | 107.1 ± 49.3 | < 0.001* |
HDL, mg/dL (mean ± SD) (Reference range: > 40) | 30.6 ± 10.9 | 34.4 ± 11.6 | < 0.001* |
WBC, 109/L (mean ± SD) (Reference range: 4000–10,000) | 7544.4 ± 2663.4 | 7717.4 ± 2897.6 | 0.347 |
CRP, mg/L (mean ± SD) (Reference range: < 10 mg/L Negative) | 67.3 ± 21.4 | 56.9 ± 20.9 | < 0.001* |
ESR, mm/1st h (mean ± SD) (Reference range: 0–15) | 54.5 ± 15.6 | 46.5 ± 15.3 | < 0.001* |
FBS, mg/dL (mean ± SD) (Reference range: 70–100) | 110.7 ± 42.9 | 105.6 ± 41.3 | < 0.001* |
Platelets × 1000/cumm (mean ± SD) (Reference range: 140,000–400,000) | 186 ± 76 | 185 ± 65 | 0.206 |
Uric acid, mg/dL (mean ± SD) (Reference range: 3.6–6.8) | 3.9 ± 1.2 | 5.6 ± 1.4 | < 0.001* |
Creatinine, mg/dL (mean ± SD) (Reference range: 0.6–1.4) | 1.2 ± 0.3 | 0.7 ± 0.2 | < 0.001* |
T3, ng/dL (mean ± SD) (Reference range: 2.3–4.2) | 3.1 ± 1.2 | 2.5 ± 0.8 | 0.061 |
T4, mcg/dL (mean ± SD) (Reference range: 5.6–13.7) | 8.9 ± 4.6 | 8.3 ± 3.3 | 0.091 |
TSH, mu/L (mean ± SD) (Reference range: 0.4–4.5) | 3.5 ± 1.4 | 3.3 ± 1.2 | 0.384 |
25-hydroxy vitamin D, ng/mL (mean ± SD) (Normal range: 21–150) | 25.3 ± 10.1 | 35.9 ± 13.4 | < 0.001* |
SARS-CoV-2 variants | < 0.001* | ||
Alpha | 396 (48.1%) | 427 (51.9%) | |
Delta | 664 (75.3%) | 218 (24.7%) | |
Omicron BA.5 | 89 (11.2%) | 697 (88.8%) | |
IFITM3 rs6598045 | < 0.001* | ||
AA | 190 (17.5%) | 897 (82.5%) | |
AG | 508 (60.6%) | 330 (39.4%) | |
GG | 451 (79.7%) | 115 (20.3%) |
COVID-19 coronavirus disease 2019, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, TG triglyceride, LDL low density lipoprotein, HDL high density lipoprotein, WBC white blood cells, CRP C-reactive protein, ESR erythrocyte sedimentation rate, FBS fasting blood glucose, T3 triiodothyronine, T4 thyroxine, TSH thyroid-stimulating hormone, SD standard deviation, SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, IFITM3 interferon-induced transmembrane protein 3.
*Statistically significant (< 0.05)