Table 2.
IFITM3 rs6598045 association with COVID-19 mortality
| Model | Genotype | Groups | OR (95% CI) | P-value | AIC | BIC | |
|---|---|---|---|---|---|---|---|
| Recovered patients (%) | Deceased patients (%) | ||||||
| Allele | A | 2124 (79.0) | 888 (39.0) | – | – | – | – |
| G | 560 (21.0) | 1410 (61.0) | – | – | – | – | |
| Codominant | A/A | 897 (66.8) | 190 (16.5) | 1.00 | < 0.0001* | 2710.2 | 2733.5 |
| A/G | 330 (24.6) | 508 (44.2) | 7.27 (5.90–8.96) | ||||
| G/G | 115 (8.6) | 451 (39.2) | 18.51 (14.31–23.96) | ||||
| Dominant | A/A | 897 (66.8) | 190 (16.5) | 1.00 | < 0.0001* | 2766.9 | 2784.4 |
| A/G-G/G | 445 (33.2) | 959 (83.5) | 10.17 (8.39–12.34) | ||||
| Recessive | A/A-A/G | 1227 (91.4) | 698 (60.8) | 1.00 | < 0.0001* | 3098.5 | 3115.9 |
| G/G | 115 (8.6) | 451 (39.2) | 6.89 (5.51–8.63) | ||||
| Overdominant | A/A-G/G | 1012 (75.4) | 641 (55.8) | 1.00 | < 0.0001* | 3336.8 | 3354.3 |
| A/G | 330 (24.6) | 508 (44.2) | 2.43 (2.05–2.88) | ||||
| Recovered patients | Deceased patients | All patients | |||||
|---|---|---|---|---|---|---|---|
| Minor allele frequency (G) | 0.21 | 0.61 | 0.41 | – | – | – | |
IFITM3: Interferon-induced Transmembrane Protein 3; COVID-19: Coronavirus disease 2019; OR: Odds ratios; CI: confidence intervals; AIC: Akaike information criterion; BIC: Bayesian information criterion
*Statistically significant (< 0.05)