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(a) RP-HPLC chromatogram showing the separation of exemestane and 17β-dihydroexemestane separation (insert panel shows the UV spectra for exemestane (blue) and 17β-dihydroexemestane (red). (b) Velocity of the conversion of exemestane to 17β-dihydroexemestane vs. substrate concentration catalyzed by the variants.
