Table 2.
Guidelines for Risk Stratification of ETE in Different Country
| ATA Risk Stratification3 | |
|---|---|
| Intermediate risk | High risk |
| Microscopic invasion of tumor into the perithyroidal soft tissues at initial surgery | Macroscopic invasion of tumor into the perithyroidal soft tissues (gross extrathyroidal extension) |
| ESMO risk stratification17 | |
| Intermediate risk | High risk |
| Microscopic invasion of perithyroidal soft tissues | Gross ETE (macroscopic invasion of perithyroidal soft tissues) Extranodal extension |
| ETA risk stratification18 | |
| Low risk | High risk |
| No Tumor invasion of locoregional tissues or structures | Tumor invasion of locoregional tissues or structures |
| UK risk stratification19 | |
| Intermediate risk | High risk |
| Microscopic invasion of tumor into the peri-thyroidal soft tissues (T3) at initial surgery | Extrathyroidal invasion |
| CSCO risk stratification20 | |
| Intermediate risk | High risk |
| Microscopic invasion of tumor into the perithyroidal soft tissues | Macroscopic invasion of tumor into the perithyroidal soft tissues |
| JAES risk stratification21 | |
| Intermediate risk | High risk |
| Not belonging to the very low-, low-, or high-risk class | Extra-thyroidal extension to adjacent structures except for the sternothyroid muscle, or extra-nodal extension of tumor in metastatic lymph node |
| National Health Commission, PRC for thyroid cancer risk stratification22 | |
| Intermediate risk | High risk |
| Minimal invasion of the perithyroidal tissue | Obvious involvement of perithyroidal soft tissue |