FIGURE 6.

Effects of glucose and nicotinic antagonists on memory during spontaneous alternation testing. Glucose enhanced memory and significantly attenuated the memory impairment produced by dihydro-beta-erythroidinem (DHβE), an α4β2 receptor antagonist. However, glucose did not reverse the impairments produced by methyllycaconitine (MLA), an α7 nicotinic receptor antagonist. The later finding suggests that α7 nicotinic receptors may act on memory downstream from glucose effects on memory. [*P < 0.05 vs. aCSF.] From Morris et al., 2012.