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. 2022 Nov 20;12:19977. doi: 10.1038/s41598-022-24170-0

Table 2.

Templates for virus-host interaction pathways.

Template name Template description*
P1 Vp – PPI – > Kp
P2 Vp – PPI – > Hp – PPI – > Kp
P3 Vp – PPI – > Hp – Act/Stab/Pr/PPM/Tr – > Kp
P4 Vp – PPI – > Hp – Exp reg – > Kg – Exp – > Kp
P5 Vp – PPI – > Hp – Expreg– > Hg – Exp– > Hp– Expreg– > Kg – Exp– > Kp
P6 Vp – PPI – > Hp – Exp reg – > Hg – Exp – > Hp – Act/Stab/Pr/PPM/Tr – > Kp
P7 Vp – PPI – > Hp – Expreg– > Hg – Exp– > Hp – PPI – > Kp

Interactions: PPI protein–protein interactions, Act/Stab/Pr/PPM/Tr regulation of activity or stability, or proteolysis, or post translational modifications, or transport (release). Exp reg regulation of gene expression. Exp gene expression (protein production).

*Objects: Vp SARS-CoV2 proteins, Kp KEGG metabolic pathway proteins, Kg KEGG metabolic pathway genes, Hp any host proteins inv olved in the interactions, Hg any host genes involved in the interactions.