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. 2022 Nov 20;12:19977. doi: 10.1038/s41598-022-24170-0

Table 4.

Statistical significance of associations between virus-host signaling pathways and KEGG metabolic processes.

Virus-host pathway template (Pi) Aminoacyl-tRNA biosynthesis (K1 = 40 proteins) Glycine, serine and threonine metabolism (K2 = 34 proteins) Arginine biosynthesis (K3 = 18 proteins)
ki1 P value ki2 P value ki3 P value
P1 3 0.092 0 0
P2 19 0.00011 11 0.26 10 0.0075
P3 3 0.23 0 2 0.99
P4 0 1 0.69 3 0.009
P5 5 0.981 10 0.049 10 0.004
P6 4 0.712 3 0.78 5 0.024
P7 19 0.0089 10 0.54 11 0.021

Significant values (p < 0.05) are in bold.

Kj is the number of proteins in KEGG metabolic pathway j, kij is the number of proteins, which represent the targets of virus-host pathway template Pi (Table 2).