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. 2022 Nov 7;9:1008447. doi: 10.3389/fvets.2022.1008447

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Copyright © 2022 Boudreau, Kerwin, DuPont, Levine and Griffin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of ROI (blue outline) and contralateral normal control (red outline) region selection for a representative example hemorrhagic CVA. The regions were selected on the T2-FLAIR transverse images and copied to the DWI and ADC series. The region of T2* hypointensity was defined on the corresponding T2* transverse image (lavender outline). Pixels that were within both the T2-FLAIR hyperintense region and the T2* hypointense region (green outline) were excluded from the resulting probability histogram (right). The histogram shows the ADC values of non-excluded pixels within the ROI, as well as the median ADC value within the contralateral control region (dotted line).