Table 1. Clinical and Biochemical Characterization of Study Subjects.
| Variables | Healthy Controls (n = 20) | SCZ (n = 40) | P Value | ||
| Mean | SD | Mean | SD | ||
| Age (years) | 32.5 | 6.8 | 33.3 | 8.1 | 0.70 |
| Male n (%) | 11 (55%) | 19 (47.5%) | 0.79 | ||
| Body mass index (kg/m2) | 25.3 | 5.3 | 23.4 | 5.5 | 0.20 |
| Systolic blood pressure (mmHg) | 122 | 13 | 116 | 14 | 0.08 |
| Diastolic blood pressure (mmHg) | 82 | 8 | 80 | 10 | 0.34 |
| Age at onset (years) | - | - | 31 | 8 | - |
| Duration of untreated illness (in months) | - | - | 17 | 16 | - |
| Total SAPS | - | - | 20 | 24 | - |
| Total SANS | - | - | 24 | 25 | - |
| Fasting plasma glucose (mg/dL) | 88 | 6 | 90 | 8 | 0.16 |
| Total cholesterol (mg/dL) | 160 | 30 | 177 | 46 | 0.16 |
| Serum triglycerides (mg/dL) | 122 | 36 | 153 | 70 | 0.07 |
| Serum HDL cholesterol (mg/dL) | 43 | 8 | 37 | 6 | 0.02* |
| Serum LDL cholesterol (mg/dL) | 101 | 23 | 100 | 32 | 0.83 |
| Serum VLDL cholesterol (mg/dL) | 27 | 9 | 29 | 13 | 0.48 |
| Cholesterol/HDL Ratio | 3.9 | 1.0 | 4.9 | 1.8 | 0.01* |
| Hemoglobin (HB) (g/dl) | 14 | 2.2 | 13 | 2.4 | 0.40 |
| Red blood cells (RBC) (*million/ul) | 5.0 | 0.4 | 5.0 | 0.6 | 0.65 |
| White blood cells (WBC) (*1000/ul) | 7.2 | 1.3 | 8.4 | 1.9 | 0.02* |
| Platelets (*1000/ul) | 293 | 88 | 295 | 82 | 0.94 |
| Lymphocytes (%) | 34 | 6.4 | 27 | 6.1 | 0.00* |
| Monocytes (%) | 6.0 | 1.2 | 5.3 | 1.3 | 0.09 |
| Eosinophils (%) | 3.5 | 2.7 | 3.6 | 3.2 | 0.91 |
| Neutrophils (%) | 55 | 6.2 | 64 | 7.8 | 0.00* |
| Neutrophil lymphocyte ratio (NLR) | 1.7 | 0.5 | 2.6 | 0.9 | 0.00* |
Abbreviations: SAPS: Scale for the Assessment of Positive Symptoms; SANS: Scale for the Assessment of Negative Symptoms; HDL: high density lipoprotein; LDL: low density lipoprotein.
Note: *statistically significant.