Table 1.
Demographic and clinical characteristics of migraine in the VBM studies.
| Authors (years) | Migraine types | Patients | Disease | Disease attacks | Health controls | |||
|---|---|---|---|---|---|---|---|---|
| M/F | Age | Duration years | years | month | M/F | Age | ||
| Neeb et al. (24) | EM | 21 (6/15) | 49.36 ± 7.62 | 26.71 ± 14.42 | NA | 5.33 ± 1.59 | 21 (6/1) | 49.40 ± 7.79 |
| CM | 21 (6/15) | 49.04 ± 7.46 | 24.43 ± 8.3 | 17.38 ± 2.66 | ||||
| Zhang et al. (16) | MWoA | 32 (8/24) | 38.3 ± 10.16 | 9.5 ± 6.23 | NA | 3.36 ± 2.55 | 32 (8/24) | 38.8 ± 10.2 |
| Bonanno et al. (25) | MWA | 14 (0/14) | 42.36 ± 2.95 | 5.21 ± 1.31 | 29.83 ± 11.9 | NA | 14 (0/14) | 42.5 ± 5.17 |
| MWoA | 14 (0/14) | 43.5 ± 3.25 | 6.78 ± 3.66 | 22.75 ± 10.03 | ||||
| Li et al. (26) | MWoA | 72 (15/57) | 21.3 (20.89; 21.73) | 66.75 (32.19; 101.31) (month) | NA | 5.89 (2.62; 9.16) | 46 (12/34) | 21.24 (20.98; 21.50) |
| Yu et al. (17) | EM | 39 (9/30) | 39.74 ± 11.59 | NA | NA | 3.75 ± 2.64 | 35 (15/20) | 34.91 ± 10.89 |
| CM | 17 (9/8) | 49.59 ± 14.64 | ||||||
| Chen et al. (19) | EM | 56 (19/37) | 37.5 ± 7.6 | 194.6 ± 116.7 (month) | NA | 13.8 ± 10.5 | 43 (15/28) | 36.2 ± 7.7 |
| CM | ||||||||
| Chou et al. (27) | Migraine | 40 (8/32) | 39.2 ± 10.05 | 14.7 ± 10.2 | NA | 9.9 ± 6.5 | 27 (6/21) | 41.3 ± 10.1 |
| Masson et al. (4) | Migraine | 19 (6/13) | 32.7 ± 8.7 | 16.8 ± 7.4 | NA | 3.3 ± 1.1 | 19 (6/13) | 33.6 ± 11.5 |
| Hubbard et al. (28) | Migraine | 17 (4/13) | 41.71 ± 12.20 | >3 (month) | NA | 4-15 | 18 (4/14) | 38.89 ± 11.25 |
| Cao et al. (29) | MWoA | 44 (11/33) | 34.93 ± 10.66 | 10.34 ± 8.98 | NA | 10.14 ± 9.68 | 32 (16/16) | 30.63 ± 9.56 |
| Schading et al. (30) | Migraine | 24 (1/23) | 38.1 ± 12.5 | 20 ± 12.0 | NA | 5.7 ± 2.5 | 30 (5/25) | 32.2 ± 10.3 |
| The technique details and main findings. | ||||||||
| Authors (years) | Diagnose criteria | Corrections | Scanners | Method | FWHM | Main findings | ||
| Neeb et al. (24) | ICHD-III beta | FWE | 3.0T | VBM | 10 | Increased: right amygdala and right putamen, left putamen, right pallidum, right hippocampus, right PHG, right superior parietal lobule, left insula, right cerebellum, left superior occipital gyrus and cuneus | ||
| Decreased: frontal lobe, right angular gyrus. | ||||||||
| Zhang et al. (16) | ICHD-III beta | FDR | 3.0T | VBM | 8 | Increased: bilateral cerebellar culmen, lingual gyrus, thalamus, fusiform and PHG | ||
| Bonanno et al. (25) | IHS | FWE | 3.0T | VBM | 8 | Increased: right superior parietal gyrus and left thalamus | ||
| Decreased: right cerebellum, left postcentral and precentral gyrus, right inferior frontal gyrus, and left lingual gyrus | ||||||||
| Li et al. (26) | ICHD-II | FWE | 3.0T | VBM | 8 | Decreased: bilateral superior and inferior colliculus, PAG, LC, median raphe nuclei (MRN) and dorsal pons medulla | ||
| Yu et al. (17) | ICHD-III beta | AlphaSim | 3.0T | VBM | 8 | Increased: PAG dlPFC, left hippocampus/PHG | ||
| Decreased: ACC, bilateral dlPFC, left hippocampus/PHG | ||||||||
| Chen et al. (19) | ICHD-III beta | FWE | 3.0T | VBM | 8 | Decreased: right orbitofrontal cortex | ||
| Chou et al. (27) | ICHD-3 | FWE | 3.0T | VBM | 8 | Increased: left PCG | ||
| Decreased: right PCG, left precentral gyrus, and cerebellum | ||||||||
| Masson et al. (4) | NA | FWE | 3.0T | VBM | 15 | Decreased: superior temporal areas and postcentral gyrus | ||
| Hubbard et al. (28) | ICHD-II | GRF | 3.0T | VBM | 8 | Increased: left hippocampus | ||
| Cao et al. (29) | ICHD-III beta | FWE | 3.0T | VBM | 8 | Decreased: middle frontal cortex | ||
| Schading et al. (30) | ICHD-III | FWE | 3.0T | VBM | 3 | Increased: left lingual gyrus | ||
ACC, anterior cingulate cortex; MWA, migraine with aura; MWoA, migraine without aura; EM, episodic migraine; CM, chronic migraine; FWHM, full width at half maximum; GRF, Gaussian random field theory; FEW, family wise error; FDR, false detect rate; SVC, small volume correction; mM, menstrual migraine; LF, low frequency; HF, high frequency; PAG, periaqueductal gray; LC, locus ceruleus; MRN, median raphe nuclei; dlPFC, bilateral dorsolateral prefrontal cortex; PHG, parahippocampal gyrus; ICHD-3 beta, international classification of headache disorders, 3rd edition (beta version); PCG, postcentral gyrus; HIS, international headache society; MTG, middle temporal gyrus; OFC, orbitofrontal cortex; T, Tesla; VBM, voxel-based morphometry.