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. 2022 Nov 7;13:1047231. doi: 10.3389/fgene.2022.1047231

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Copyright © 2022 Ding, Li, Zhang, He and Su.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunoassay of two clusters. The expression level of PD-L1 between normal and tumor tissues (A), between cluster 1 and cluster 2 (B). The correlation between PD-L1 expression and expression of 10 NETs-associated lncRNA (C). The expression level of CTLA4 between normal and tumor tissues (D), between cluster 1 and cluster 2 (E). The correlation between CTLA4 expression and expression of 10 NETs-associated lncRNAs (F). The difference in ESTIMATE score, immune score and stromal score between cluster 1 and cluster 2 (G–I). Immunephenoscores (IPS) analysis (J–M). The abundance of immune infiltration cells in cluster 1 and cluster 2 (N) (* p < 0.05, ** p < 0.01, *** p < 0.001).