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. 2022 Nov 7;13:1053330. doi: 10.3389/fmicb.2022.1053330

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Copyright © 2022 Zhou, Yong, Zhu, Yang and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of exogenous D-ribose on membrane potential. (A) Variation of PMF in SCH-R by D-ribose dose with or without CCCP. (B) Variation of PMF in SR-7 by D-ribose dose with or without CCCP. (C) Intracellular concentration of gentamicin in SCH-R and clinical isolates in the presence of 24 mM D-ribose. (D) Intracellular concentration of gentamicin in SCH-R and clinical isolates in the presence of 24 mM D-ribose with or without CCCP. GEN, gentamicin. (E) Percent survival of SCH-R and clinical isolates in the presence or absence of CCCP and 1 MIC gentamicin plus 24 mM D-ribose. GEN, gentamicin. Results are displayed as the mean ± SEM and three biological repeats are carried out. Significant differences are identified (*p < 0.05 and **p < 0.01).