TABLE 4.
BUT change from baseline | ||||||||
---|---|---|---|---|---|---|---|---|
Treatment-emergent AEs | Placebo | −0.02 (−1.04, 1.01) | −0.13 (−0.78, 0.52) | −0.35 (−1.34, 0.64) | −0.44 (−0.92, 0.05) | −0.62 (−1.10,−0.14) | −0.74 (−1.84, 0.36) | −0.99 (−1.52,−0.46) |
2.41 (−3.78, 8.60) | Clacier® | −0.12 (−1.33, 1.10) | −0.33 (−1.76, 1.09) | −0.42 (−1.55, 0.71) | −0.60 (−1.74, 0.53) | −0.72 (−2.22, 0.78) | −0.98 (−2.13, 0.18) | |
N/A | N/A | CyclASol® | −0.22 (−1.40, 0.97) | −0.30 (−1.12, 0.51) | −0.49 (−1.22, 0.25) | −0.60 (−1.84, 0.63) | −0.86 (−1.70, −0.02) | |
2.55 (−4.02, 9.12) | 0.14 (−8.89, 9.16) | N/A | Zirun® | −0.09 (−1.19, 1.01) | −0.27 (−1.37, 0.83) | −0.39 (−1.87, 1.09) | −0.64 (−1.77, 0.48) | |
N/A | N/A | N/A | N/A | Cequa® | −0.18 (−0.88, 0.52) | −0.30 (−1.51, 0.92) | −0.55 (−1.27, 0.16) | |
1.90 (−0.26, 4.06) | 0.51 (−6.04, 7.07) | N/A | 0.65 (−5.55, 6.85) | N/A | Restasis® | −0.12 (−1.10, 0.86) | −0.37 (−1.10, 0.35) | |
2.62 (−2.33, 7.57) | 0.21 (−7.71, 8.13) | N/A | 0.07 (−7.56, 7.71) | N/A | 0.72 (−3.73, 5.17) | TJ Cyporin® | −0.26 (−1.48, 0.97) | |
0.27 (−4.10, 4.63) | 2.14 (−5.43, 9.71) | N/A | 2.28 (−5.61, 10.16) | N/A | 1.63 (−3.24, 6.50) | 2.35 (−4.25, 8.95) | Ikervis® |
Each cell contains the odds ratio (OR) and 95% confidence interval for BUT changes and TEAEs; the comparison should be read from left to right. Bold numbers indicate statistically significant differences. BUT score change from baseline, ST score change from baseline; N/A, data not available.