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. 2022 Nov 5;25(12):105513. doi: 10.1016/j.isci.2022.105513

Figure 5.

Figure 5

STOC-T imaging of retinal microstructure

Montaged (stitched) retinal images (9 mm × 4.6 mm) of macula and optic nerve head; and panels with zoomed-in regions.

(A) 15 μm en face projection of the inner retinal layers featuring the optic nerve discs, retinal nerve fiber layer (NFL), and retinal ganglion cell layer (GCL) in one image.

(B) Cross-sectional image along the papillomacular axis of the human retina, indicated by red line in panel (A);

(C–F) Details of the inner limiting membrane (ILM), NFL, and intermediate capillary plexus (ICP) are shown as thin layers (of 5 μm) and zoomed-in for the locations indicated by the dashed green boxes in (A);

(G) STOC-T reconstruction of 15 μm thick coronal projection of the junction between inner and outer segments of photoreceptors (IS/OS); the red box in the IS/OS image is shown zoomed-in to various degrees on the right. The IS/OS reconstruction was numerically compensated for ocular aberrations revealing photoreceptor structure (22nd order Zernike polynomials).