Table 1.

Overview of data available from El Salvador and Nicaragua cohort studies^14–17

Exploratory dataset, El Salvador, WE Project
Preharvest	Week									End-harvest
	2	4	6	8	10	12	14	16	18
Questionnaire, 2-week recall
Symptoms	X	X	X	X	X	X	X	X	X	X
Biomarker, preshift and postshift
Dipstick: SpG, RBCs, WBCs, protein	X	X	X	X	X	X	X	X	X	X
eGFR			X				X			X
CRP			X				X			X
WBC			X				X			X
Hb			X				X			X
Confirmation dataset, Nicaragua, Adelante
Preharvest	Cross-harvest									End-harvest
	Routine random monitoring of workers			Mid-harvest, ~week 10			Routine random monitoring of workers
eGFR	Dipsticks preshift and postshift as part of hydration monitoring (specific gravity). Leukocyturia is recorded			Creatinine screening aiming to identify workers with kidney injury for rest or ending or changing employment			Dipsticks preshift and postshift as part of hydration monitoring (specific gravity). Leukocyturia is recorded			eGFR

RBCs=haematuria, WBCs=leukocyturia.

CRP, C reactive protein; eGFR, estimated glomerular filtration rate; Hb, haemoglobin; RBC, red blood cell; SpG, specific gravity; WBC, white blood cell; WE, Worker Health and Efficiency.