Table 3.
Characteristics and laboratory data of patients presenting with DKA as a complication of diagnosed T1DM with newly diagnosed T1DM
| Diagnosis time | p | ||
|---|---|---|---|
| Features | New diagnose (n=39) | Known diagnose (n=16) | |
| Hospital stay, median (min–max) | 3.0 (1.0–34.0) | 3.0 (1.0–31.0) | 0.775 |
| Mechanical ventilation (n,%) | |||
| Yes (n=6) | 4 (66.7) | 2 (33.3) | |
| No (n=49) | 35 (71.4) | 14 (28.6) | 1.00 |
| Laboratory findings, median (min–max) | |||
| Glucose (mg/dl) | 411.0 (233.0–946.0) | 394.5 (232.0–759.0) | 0.566 |
| HbA1c (%) | 12.9 (9.0–16.4) | 10.7 (6.6–14.7) | 0.002 |
| pH | 7.02 (6.09–7.27) | 7.02 (6.82–7.30) | 0.882 |
| Lactate (mmol/l) | 1.6 (0.5–13.9) | 2.3 (0.6–7.7) | 0.115 |
| HCO3 (mmol/l) | 5.9 (1.0–19.0) | 6.4 (3.7–20.0) | 0.956 |
| Procalcitonin (µg/l) | 0.54 (0.03–177.0) | 3.21 (0.05–15.5) | 0.064 |
| CRP (mg/dl) | 2.63 (0.01–30.2) | 3.38 (0.01–118.0) | 0.649 |
| AST (U/l) | 14.0 (7.3–41.0) | 21.7 (7.0–121.0) | 0.035 |
| ALT (U/l) | 10.7 (5.0–37.1) | 16.4 (5.0–71.0) | 0.009 |
| LDH (U/l) | 222.0 (123.0–383.0) | 240.0 (154.0–861.0) | 0.266 |
| Albumin (g/l) | 41.9 (3.6–51.8) | 43.5 (5.1–197.0) | 0.278 |
| WBC (103 U/l) | 16.15 (3.67–37.0) | 23.35 (9.10–51.49) | 0.021 |
| Neutrophil (103 U/l) | 12.15 (2.5–29.4) | 18.65 (5.27–45.0) | 0.020 |
| Lymphocyte (103 U/l) | 2.63 (1.18–63.0) | 2.87 (1.27–6.80) | 0.704 |
| Platelet (103 U/l) | 299.0 (173.0–540.0) | 340.5 (180.0–501.0) | 0.326 |
| Hemoglobin (g/dl) | 13.3 (9.8–17.1) | 14.2 (11.2–16.6) | 0.221 |
| Na (mmol/l) | 137.0 (122.0–151.0) | 137.0 (128.0–145.0) | 1.00 |
| K (mmol/l) | 3.7 (2.9–114.0) | 4.8 (3.1–6.0) | 0.003 |
| Na (24 h) | 139.0 (133.0–156.0) | 139.0 (132.0–149.0) | 0.985 |
| K (24 h) | 3.3 (2.5–5.05) | 3.9 (3.1–4.6) | 0.005 |
| Glucose (24 h) | 188.0 (94.0–320.0) | 185.0 (133.0–448.0) | 0.970 |
| pH (24 h) | 7.36 (7.0–7.45) | 7.35 (7.20–7.43) | 0.717 |
| HCO3 (24 h) | 17.3 (12.0–30.0) | 18.2 (12.1–28.6) | 0.475 |
DKA: Diabetic ketoacidosis; T1DM: Type 1 diabetes mellitus; HCO3: Actual bicarbonate value in blood gas analysis; CRP: C-reactıve proteın value; AST: Aspartate amino transferase; ALT: Alanine amino transferase; LDH: Lactate dehydrogenase; WBC: White blood cell count; Na: Serum sodium value; K: Serum potassium value.