Figure 1.

Hazard ratios of CVD, ESKD, all-site cancer, all-site infection, and all-cause mortality in people with prediabetes stratified by age groups. All p-values for interaction test are statistically significant. Model 1: adjusting for baseline age, sex, and calendar year. Model 2: model 1 + excluding subsequent development of diabetes. Model 3: model 2 + further adjustment of metabolic factors including baseline LDL-C, triglyceride/HDL-C, haemoglobin, albumin, use of lipid-regulating drugs and blood pressure medications. CVD: cardiovascular disease; ESKD: end-stage kidney disease; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.