Table 2.
Stereotactic radiosurgery treatment variables
| Variable | All patients (n = 305) | Seizure (n = 26) | Nonseizure (n = 279) | P value |
|---|---|---|---|---|
| Number of treated lesions, median (range) | 1.0 (1.0, 3.0) | 3.0 (1.0, 4.0) | 1.0 (1.0, 3.0) | .018 |
| Fractionated radiation, n (%) | 90 (29.5) | 14 (53.8) | 76 (27.2) | .007 |
| Total irradiated volume (cm3), median (IQR) | 4.1 (1.1, 12.8) | 12.5 (3.6, 37.3) | 3.7 (0.9, 11.4) | <.001 |
| Maximum single lesion volume (cm3), median (IQR) | 3.1 (0.7, 11.3) | 8.8 (2.7, 25.9) | 2.8 (0.7, 11.2) | .003 |
| Maximum single lesion diameter (cm), median (IQR) | 2.1 (1.3, 3.5) | 3.2 (2.0, 4.4) | 2.0 (1.3, 3.4) | .003 |
| Steroids post-SRS, n (%) | 135 (44.3) | 20 (76.9) | 115 (41.2) | .001 |
| AEDs post-SRS, n (%) | 27 (8.9) | 11 (42.3) | 16 (5.7) | <.001 |
Abbreviations: AED = antiepileptic drug; IQR = interquartile range; SRS = stereotactic radiosurgery.
Values in boldface are statistically significant.