Table 3.
Baseline demographics, pretreatment clinical courses, and radiation variables for patients who received craniotomy before stereotactic radiosurgery
| Variable | All patients (n = 78) | Seizure (n = 9) | Nonseizure (n = 69) | P value |
|---|---|---|---|---|
| Age, median (IQR) | 62.0 (55.0, 69.0) | 57.0 (49.0, 63.0) | 64.0 (56.0, 69.0) | .114 |
| Female sex, n (%) | 51 (65.4) | 5 (55.6) | 46 (66.7) | .711 |
| KPS pre-SRS, median (IQR) | 80.0 (80.0, 90.0) | 80.0 (80.0, 90.0) | 80.0 (70.0, 90.0) | .510 |
| Number of treated lesions, median (range) | 1.0 (1.0, 2.0) | 1.0 (1.0, 3.0) | 1.0 (1.0, 2.0) | .192 |
| Pre-SRS immunotherapy, n (%) | 8 (10.3) | 1 (11.1) | 7 (10.1) | 1.0 |
| Pre-SRS chemotherapy, n (%) | 16 (20.5) | 3 (33.3) | 13 (18.8) | .38 |
| Total irradiated volume, median (IQR) | 21.7 (11.2, 35.3) | 37.9 (33.8, 54.1) | 19.2 (11.0, 33.1) | <.001 |
| Maximum lesion target diameter, median (IQR) | 4.2 (3.4, 5.1) | 4.9 (4.4, 5.5) | 4.0 (3.3, 5.0) | .048 |
Abbreviations: IQR = interquartile range; KPS = Karnofsky Performance Scale score; SRS = stereotactic radiosurgery.
Values in boldface are statistically significant.