Fig. 5.

TATE is associated with infiltration of immunosuppressive T cells in HNSCC. A, the list of surface markers in each subgraph. The color of fluorescence for each surface marker was shown on the right side. B-C, representative images of multiplex immunofluorescence of surface markers of TILs in TATE-poor and TATE-enriched ROIs. Scale bar: upper, 100um; lower, 20um. D-J, automated quantification of percentage of specific component of TILs in total lymphocytes in TATE-enriched (TATE/ stromal cells >5%), TATE-medium (TATE/ stromal cells 1-5%) and in TATE-poor (TATE/ total stromal cells <1%) ROIs. Arterisk: p<0.05.