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. Author manuscript; available in PMC: 2022 Nov 21.

Published in final edited form as: J Urol. 2020 Dec 24;205(5):1352–1360. doi: 10.1097/JU.0000000000001547

Table 2.

Detection of Gleason grade progression for MRI-targeted biopsy compared to systematic biopsy

	2 Yrs (277 pts)			4 Yrs (130 pts)			6+ Yrs (80 pts)
Grade Progression	MRI-Targeted Biopsy	Systematic Biopsy	p Value	MRI-Targeted Biopsy	Systematic Biopsy	p Value	MRI-Targeted Biopsy	Systematic Biopsy	p Value

GG1–≥GG2 (No.)	23.4% (44)	15.4% (29)	0.029	31.4% (32)	22.5% (23)	0.12	34.7% (25)	26.4% (19)	0.18
GG2–≥GG3 (No.)	32.6% (29)	16.9% (15)	0.006	17.9% (5)	21.4% (6)	1	25.0% (2)	37.5% (3)	1
All progression (No.)	26.4% (73)	15.9% (44)	<0.001	28.5% (37)	22.3% (29)	0.20	33.8% (27)	27.5% (22)	0.30

Grade progression detection difference was significant at 2 years (p <0.001).