Fig. 4.

Heatmap and 2-way semi-supervised hierarchical clustering based on 46 differentially expressed miRNAs (fold-change >1.5 and p < 0.05, q=0.15) between initial diagnostic skin biopsies from 154 patients with early-stage mycosis fungoides (MF) (red) and skin biopsies from 16 patients with untreated psoriasis (yellow). Expression levels are z-scaled and range from high (red) to low (green). Grey spots indicate missing (below lower level of detection) values. Note: incomplete separation of MF from psoriasis lesions.