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. 2022 Nov 15;31:e81. doi: 10.1017/S2045796022000658

Table 3.

Summary statistics and results from mixed model analysis of primary and secondary outcomes

Descriptive statistics Mixed model analysis
Primary and secondary outcomes Visit gPM + (n = 168) EUC (n = 189) Difference in LS mean (95% CI) p-value Effect size
Estimated mean (s.e.) Estimated mean (s.e.)
HSCL-25 Depression Baseline 36.57 (0.67) 35.15 (0.67)
6-week 29.95 (0.72) 32.44 (0.69) 3.92 (1.84–5.99) 0.001 0.43
3 months 29.03 (0.73) 31.28 (0.69) 3.68 (1.54–5.81) 0.001 0.40
12 months 28.26 (0.78) 25.85 (0.73) −0.98 (−3.23 to 1.26) 0.39 −0.11
HSCL-25 Anxiety Baseline 24.82 (0.46) 25.00 (0.46)
6-week 20.42 (0.49) 21.95 (0.47) 1.35 (−0.22 to 2.93) 0.09 0.22
3 months 20.03 (0.50) 19.64 (0.47) −0.57 (−2.21 to 1.06) 0.49 −0.09
12 months 19.34 (0.54) 17.85 (0.50) −1.67 (−3.39 to 0.04) 0.06 −0.27
WHODAS 2.0 Baseline 23.53 (0.47) 23.92 (0.47)
6-week 14.70 (0.49) 15.63 (0.51) 0.87 (−1.4 to 2.22) 0.53 0.17
3 months 15.73 (0.50) 14.98 (0.51) −1.14 (−2.96 to 0.69) 0.22 −0.23
12 months 15.16 (0.56) 13.81 (0.53) −1.74 (−3.67 to 0.19) 0.08 −0.35
PCL-5 Baseline 25.98 (0.91) 26.72 (0.90)
6-week 16.07 (0.98) 17.54 (0.93) 0.73 (−2.52 to 3.98) 0.66 0.05
3 months 10.29 (0.99) 10.32 (0.94) 0.01 (−3.97 to 2.54) 0.67 0.00
12 months 2.60 (1.07) 3.29 (1.00) −0.06 (−3.48 to 3.36) 0.97 0.00
PSYCHLOPS Baseline 16.48 (0.31) 15.72 (0.31)
6-week 13.35 (0.33) 13.68 (0.32) 1.08 (0.18–1.99) 0.02 0.28
3 months 13.49 (0.34) 13.60 (0.32) 0.87 (−0.11 to 1.84) 0.08 0.22
12 months 12.45 (0.36) 11.77 (0.34) 0.07 (−0.95 to 1.10) 0.89 0.02
PG-13 Baseline 27.97 (0.85) 29.19 (0.87)
6-week 26.83 (0.90) 27.73 (0.91) −0.32 (−3.06 to 2.43) 0.82 −0.03
3 months 20.48 (0.92) 21.42 (0.91) −0.28 (−3.20 to 2.63) 0.85 −0.03
12 months 19.71 (0.99) 19.79 (0.99) −1.15 (−4.26 to 1.96) 0.47 −0.12
PQ-B Baseline 13.33 (0.15) 13.41 (0.15)
6-week 14.84 (0.16) 14.44 (0.16) −0.53 (−1.10 to 0.04) 0.07 −0.18
3 months 15.07 (0.17) 14.96 (0.16) −0.24 (−0.82 to 0.33) 0.41 −0.08
12 months 15.88 (0.18) 15.79 (0.17) −0.19 (−0.81 to 0.43) 0.55 −0.07
APQ: Involvement Baseline 34.96 (0.82) 34.56 (0.82)
6-week 33.75 (0.88) 32.95 (0.85) −0.39 (−3.46 to 2.67) 0.80 −0.04
3 months 31.90 0.90) 31.86 (0.85) 0.37 (−2.898 to 3.62) 0.83 0.04
12 months 34.41 0.90) 37.26 (0.91) 3.25 (−0.08 to 6.58) 0.06 0.38
APQ: Supervision Baseline 14.97 (0.34) 14.81 (0.34)
6-week 12.91 (0.37) 13.54 (0.35) 0.78 (−0.46 to 2.02) 0.21 0.16
3 months 12.42 (0.38) 12.42 (0.36) 0.16 (−1.188 to 1.50) 0.82 0.03
12 months 13.34 (0.41) 12.23 (0.38) −0.95 (−2.35 to 4.64) 0.19 −0.20
APQ: Positive parenting Baseline 24.08 (0.43) 24.62 (0.42)
6-week 23.45 (0.46) 23.59 (0.44) −0.40 (−1.949 to 1.14) 0.61 0.08
3 months 21.86 (0.47) 22.26 (0.45) −0.14 (−1.76 to 1.48) 0.86 −0.03
12 months 24.19 (0.51) 22.73 (0.47) −2.01 (−3.70 to −0.31) 0.02 −0.41
APQ: Discipline Baseline 15.49 (0.32) 14.74 (0.32)
6-week 13.73 (0.34) 13.52 (0.33) 0.54 (−0.70 to 1.79) 0.39 0.14
3 months 13.00 (0.35) 13.57 (0.33) 1.33 (0.17–2.49) 0.03 0.33
12 months 13.29 (0.38) 12.36 (0.35) −0.17 (−1.40 to 1.05) 0.78 −0.04
APQ: Punishment Baseline 6.08 (0.15) 6.34 (0.15)
6-week 5.49 (0.16) 5.55 (0.16) −0.09 (−0.71 to 0.31) 0.44 −0.03
3 months 5.41 (0.17) 5.47 (0.16) −0.27 (−0.79 to 0.31) 0.31 −0.10
12 months 5.54 (0.18) 5.34 (0.17) −0.46 (−1.01 to 0.13) 0.10 −0.17
PSC: Total score Baseline 14.79 (0.49) 16.22 (0.48)
6-week 13.01 (0.54) 13.99 (0.52) −0.46 (−2.09 to 1.19) 0.59 −0.06
3 months 12.43 (0.53) 13.35 (0.53) −0.52 (−2.23 to 1.20) 0.56 −0.08
12 months 16.84 (0.62) 17.28 (0.56) −1.00 (−2.87 to 0.87) 0.30 −0.14
PSC: Attention problems Baseline 3.89 (0.16) 4.45 (0.16)
6-week 3.42 (0.17) 3.83 (0.17) −0.22 (−0.77 to 0.34) 0.44 −0.10
3 months 3.14 (0.18) 3.77 (0.17) −0.23 (−0.82 to 0.37) 0.46 −0.10
12 months 2.05 (0.20) 3.48 (0.17) −0.35 (−1.00 to 0.30) 0.30 −0.16
PSC: Internalising Baseline 3.22 (0.11) 3.35 (0.11)
6-week 2.84 (0.12) 2.97 (0.12) 0.01 (−0.38 to 0.40) 0.96 0.00
3 months 2.85 (0.12) 3.01 (0.12) 0.04 (−0.38 to 0.45) 0.87 0.03
12 months 2.66 (0.14) 2.63 (0.13) −0.16 (−0.61 to 0.29) 0.49 −0.10
PSC: Externalising Baseline 3.63 (0.11) 3.64 (0.11)
6-week 3.30 (0.12) 3.30 (0.12) −0.01 (−0.43 to 0.41) 0.96 0.00
3 months 3.20 (0.12) 3.37 (0.12) 0.17 (−0.25 to 0.59) 0.43 0.11
12 months 3.04 (0.14) 2.88 (0.13) −0.17 (−0.62 to 0.28) 0.46 −0.11

EUC, Enhanced usual care; LS, Least Square; HSCL, Hopkins Symptom Checklist (depression subscale score range: 10–40; anxiety subscale score range: 15–60; higher scores indicate elevated anxiety or depression); PQ-B, Brief Prodromal Questionnaire; WHODAS 2.0, WHO Disability Assessment Schedule 2.0 (total score range: 0–48; higher scores indicate more severe impairment); PCL-5, Posttraumatic Stress Disorder Checklist (total score range: 0–80; higher scores indicate more severe PTSD severity); PSYCHLOPS, Psychological Outcomes Profiles (total score range: 0–20; higher scores indicate poorer outcome); PG-13, Prolonged Grief Disorder 13 (total score range: 11–57; higher scores indicate poorer outcome); PQ, Prodromal Questionnaire; (total score range: 0–64; higher scores indicate poorer outcome); APQ, Alabama Parenting Questionnaire (Parental Involvement subscale score range: 10–50; Positive Parent subscale score range (total score range : 6–30; higher scores indicate poorer outcome); Supervision subscale score range 10–50; Discipline subscale score range 6–30; Punishment subscale score range 3–15; higher scores indicate elevated parental involvement, positive parenting, supervision, discipline and punishment). Paediatric Symptom Checklist is child's self-report (PSC; Attention Problems subscale score range: 0–10; Internalising subscale score range: 0–10; Externalising subscale score range: 0–14). Effect size was calculated by the difference in least square means between intervention and EUC from mixed model divided by the pooled standard deviation.