Table 3.
Factors associated with high FIB-4 index
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95%CI) | P value | OR (95%CI) | P value | |
| Sex (Male vs. Female) | 0.740 (0.468-1.170) | 0.198 | ||
| Smoking | 0.318 (0.138-0.734) | 0.007 | ||
| Habitual drinking | 2.338 (1.381-3.956) | 0.002 | ||
| Obesity | 1.034 (0.619-1.728) | 0.899 | ||
| Large waist circumference | 1.456 (0.903-2.347) | 0.123 | ||
| Hypertension | 8.217 (4.721-14.302) | < 0.001 | 9.040 (4.081-20.024) | < 0.001 |
| Diabetes mellitus | 5.935 (3.454-10.200) | < 0.001 | 4.251 (1.773-10.193) | 0.001 |
| Dyslipidemia | 1.354 (0.861-2.131) | 0.190 | ||
| Albumin | 0.268 (0.087-0.828) | 0.022 | 0.265 (0.083-0.841) | 0.024 |
| GGT | 1.006 (1.003-1.008) | < 0.001 | ||
| White blood cell | 0.999 (0.999-1.000) | < 0.001 | 0.999 (0.999-1.000) | < 0.001 |
| Hemoglobin | 0.919 (0.799-1.058) | 0.240 | ||
| Creatinine | 1.218 (0.903-1.643) | 0.197 | ||
BMI Body mass index, FIB-4 Fibrosis-4, GGT Gamma-glutamyl transpeptidase