Table 2.
CMR characteristics in patients with ES and normal controls
| Healthy controls (n = 30) | ES patients (n = 45) | P-value | |
|---|---|---|---|
| Left ventricle, LV | |||
| LV EDVI, mL/m2 | 78 ± 13 | 82 ± 30 | 0.512 |
| LV ESVI, mL/m2 | 29 ± 7 | 39 ± 17 | 0.001 |
| LVEF, % | 62.7 ± 4.0 | 52.9 ± 7.9 | < 0.001 |
| LV mass index, g/m2 | 45 ± 8 | 565 ± 18 | 0.002 |
| LV SVI, mL/m2 | 31 ± 5 | 39 ± 12 | < 0.001 |
| Right ventricle, RV | |||
| RV EDVI, mL/m2 | 73 ± 13 | 122 ± 57 | < 0.001 |
| RV ESVI, mL/m2 | 30 ± 9 | 78 ± 47 | < 0.001 |
| RVEF, % | 59 ± 7 | 36 ± 13 | < 0.001 |
| RV SVI, mL/m2 | 26 ± 4 | 41 ± 14 | < 0.001 |
| RV EDV/LV EDV | 0.9 ± 0.1 | 1.5 ± 0.9 | < 0.001 |
| RV ESV/LV ESV | 1.0 ± 0.2 | 2.3 ± 1.8 | < 0.001 |
| Diffuse myocardial fibrosis | |||
| Native T1, ms | 1209 ± 40 | 1266 ± 76 | < 0.001 |
| ECV, % | 25.6 ± 2.2 | 28.6 ± 5.9 | 0.004 |
| LGE presence, n (%) | |||
| Anterior/inferior VIP | – | 43 (95.6%) | – |
| Any myocardium* | – | 16 (35.6%) | – |
| Septum | – | 12 (26.7%) | – |
| RV myocardium | – | 10 (22.2%) | – |
| LV myocardium | – | 3 (6.7%) | – |
| RV trabeculae | – | 3 (6.7%) | – |
| LV papillary | – | 1 (2.2%) | – |
ES Eisenmenger syndrome, CMR cardiovascular magnetic resonance, LV left ventricular, RV right ventricular, EDVI end-diastolic volume index, ESVI end-systolic volume index, EF ejection fraction, massi mass index, SVI stroke volume index, ECV extracellular volume, LGE late gadolinium enhancement, VIP ventricular insertion point
*Excluding anterior and inferior VIP
Values in bold indicate P values < 0.05