Table 1.

Bivariable and Multivariable Cox regression analysis of predictors of Death among HIV infected under five children receiving ART in West Amhara Referral Hospitals between January 2010 and December 2019

Variable	Category of Variables	Outcome status		CHR [95%CI]	AHR[95%CI]	P-value
		Death	Censored
Age of the child	< 12 months	3	28	2.40(0.71, 8.08)	2.17(0.47, 10.02)	0.321
	12 -59 months	22	362	1	1
Age of caregiver	18–30 years	9	179	1	1
	31–40 years	9	150	1.22(0.48, 3.08)	0.58(0.18, 1.82)	0.347
	41–50 years	3	41	2.28(0.61, 8.56)	1.20(0.24, 6.05)	0.824
	> 50 years	4	20	7.88(2.35, 26.48)*	0.76(0.14, 4.19)	0.754
Status of parents	Both alive	17	304	1	1
	mother alive but father dead	2	29	1.31(0.30, 5.67)	0.86(0.16, 4.63)	0.859
	Mother dead, but father alive	3	13	4.16(1.2, 14.25)*	1.72(0.37, 8.13)	0.491
	Both dead	3	44	2.34(0.68, 8.11)	0.75(0.16, 3.46)	0.715
Residence	Urban	11	274	1	1
	Rural	14	116	3.85(1.73, 8.58)*	3.32(1.17, 9.39)	0.024**
OI at baseline	Yes	22	239	4.52(1.35, 15.12)*	1.79(0.35, 9.11)	0.483
	No	3	151	1	1
CD4 count or percent	Above the threshold	5	179	1	1
	Below the threshold	20	211	2.28(0.91, 5.73)*	0.96(0.32, 2.91)	0.942
ART adherence status	Good	11	308	1	1
	Fair	6	51	3.04 (1.12, 8.22)	1.88(0.53,6.7)	0.329
	Poor	8	31	6.00(2.40, 15.01)*	3.36(1.06, 10.69)	0.040**
CPT	Yes	20	352	1	1
	No	5	38	4.50(1.66, 12.19)*	1.81(0.50,6.58)	0.366
IPT	Yes	6	192	1	1
	No	19	198	4.67(1.86, 11.75)*	3.15(1.11, 8.94)	0.031**
OI’s during follow up	Yes	19	159	2.79(1.11, 7.049)*	1.51(0.52, 4.34)*	0.446
	No	6	231	1	1
Baseline hemoglobin(Hgb)	Anemic(< 10 g/dl)	12	39	7.40(3.37, 16.23)*	3.05 (1.16, 8.03)	0.024**
	Nonanemic(≥ 10 g/d)	13	351	1	1
Baseline WHO Clinical Stages	Mild (stage I & II)	5	218	1	1
	Advanced (stage III&IV)	20	172	5.00(1.88, 13.36)*	1.15(0.27, 4.86)	0.845