Table 3.
The crude and adjusted association between the measured characteristics of fertility clinics' attendees with being of seropositive to HSV-2 IgG antibodies.
| Crude OR | Age-adjusted OR | |
|---|---|---|
| Age—years, continuous | 1.1 (1.0–1.2)** | – |
| 19–30 | 1.00 | – |
| 31–40 | 1.8 (0.6–5.6) | – |
| 41–54 | 4.3 (1.4–13.4)* | – |
| Sex | ||
| Male | 1.00 | 1.00 |
| Female | 0.7 (0.3–2.0) | 0.8 (0.3–2.3) |
| Nationality | ||
| Middle East | 1.00 | 1.00 |
| Others | 0.6 (0.1–2.5) | 0.5 (0.1- 2.3) |
| Africa | 2.7 (0.5–14.3) | 2.4 (0.4–13.7) |
| America, Asia, and Europe | NA | NA |
| Education | ||
| Secondary and belowa | 1.00 | 1.00 |
| College level and higher | 0.6 (0.3–1.3) | 0.6 (0.3–1.3) |
| BMI kg/m2 continuous | 1.0 (0.9–1.1) | 1.0 (0.9–1.1) |
| Normal | 1.00 | 1.00 |
| Overweight | 1.8 (0.7–4.3) | 1.4 (0.6–3.5) |
| Obese | 1.5 (0.6–3.8) | 1.1 (0.4–2.9) |
| Underweight | NA | NA |
| Overweight and obese | 1.6 (0.7–3.6) | 1.3 (0.6–2.9) |
| Marriage duration | ||
| Less than a year | 1.00 | 1.00 |
| 1–5 years | 0.9 (0.2–3.3) | 0.9 (0.2–3.6) |
| More than 5 years | 0.8 (0.2–2.9) | 0.5 (0.1–2.1) |
| Chronic co–morbidity | ||
| No | 1.00 | 1.00 |
| At least one | 0.5 (0.2–1.5) | 0.5 (0.2–1.3) |
| Diabetes Mellitusb | 1.9 (0.6–6.1) | 1.3 (0.4–4.4) |
| Cardiovascular disordersc | – | |
| Respiratory diseasesd | – | |
| Rheumatic arthritis | – | |
| Thyroid dysfunctione | 1.0 (0.1–7.9) | 0.7 (0.1–5.6) |
| Other chronic diseasesf | 0.5 (0.1–3.9) | 0.5 (0.1–4.5) |
| Ever had urinary tract infection | ||
| No | 1.00 | 1.00 |
| Yes | 0.6 (0.2–1.9) | 0.5 (0.2–1.9) |
| Ever had genital infection | ||
| No | 1.00 | 1.00 |
| Yes | 1.4 (0.6–3.2) | 1.5 (0.6–3.3) |
| Frequency of genital infection | ||
| Once | 1.00 | 1.00 |
| More than once | 1.2 (0.3–5.6) | 1.4 (0.3–6.5) |
| Genital infection symptoms occurrenceg | ||
| No | 1.00 | 1.00 |
| At least one | 1.2 (0.6–2.6) | 1.2 (0.6–2.7) |
| History of pregnancy lossh | ||
| No | 1.00 | 1.00 |
| Yes | 1.4 (0.7–3.0) | 1.2 (0.6–2.5) |
| Yes, once | 1.5 (0.6–3.7) | 1.5 (0.6–3.6) |
| Yes, recurrent loss | 1.4 (0.5–3.4) | 1.0 (0.4–2.6) |
| History of ectopic pregnancyh | ||
| No | 1.00 | 1.00 |
| Yes | 0.8 (0.2–2.9) | 0.8 (0.2–2.7) |
| Yes, once | 0.6 (0.1–2.6) | 0.6 (0.1–2.5) |
| Yes, recurrent | 3.6 (0.3–40.4) | 2.5 (0.2–28.9) |
| Type of infertility | ||
| Primary | 1.00 | 1.00 |
| Secondary | 1.6 (0.7–3.5) | 1.3 (0.6–2.8) |
| Infertility duration | ||
| < 3 months | 1.00 | 1.00 |
| 3–6 months | 1.9 (0.6–6.5) | 2.1 (0.6–7.5) |
| 6–12 months | 1.6 (0.4–6.2) | 1.7 (0.4–6.7) |
| >12 months | 1.0 (0.3–2.8) | 0.7 (0.2–2.2) |
| ≥6 months | 1.1 (0.4–3.1) | 0.9 (0.3–2.5) |
| Infertility causesi | ||
| Male infertility/Other or unspecified | 1.00 | 1.00 |
| Female infertility of other or unspecified origin | 0.7 (0.2–2.3) | 0.8 (0.2–2.4) |
| Female infertility associated with anovulation | – | – |
| Female infertility of tubal origin | – | – |
| Female infertility of uterine origin | 2.8 (0.2–38.0) | 4.2 (0.3–64.6) |
| Semen analysisj | ||
| Normal | 1.00 | 1.00 |
| Abnormal | 1.4 (0.1–14.7) | 2.1 (0.2–23.7) |
a
Five patients reported no schooling.
b
Diabetes Mellitus of any type including GDM.
c
Cardiovascular disorders of any type including high blood pressure.
d
Chronic respiratory diseases include OCPD, asthma and TB.
e
Thyroid dysfunctions of any type.
f
Other chronic diseases include cancer, allergy, anemia, PCOS, PMDD.
g
Currently or during the past 3 months,
h
Sample size includes females only (N = 255),
i
According to ICD codes.
j
Reported in medical records.
*
p < 0.05,
**
p < 0.001.