Table 2.

The correlation between clinicopathological characteristics and HPV/EBV/MMTV-like virus status (the HPV/EBV/MMTV-like virus positive group was compared with other subgroups of breast cancer with various HPV/EBV/MMTV-like virus statuses)

Clinicopathological characteristics	HPV+/EBV+/MMTV-like virus+ (%)	HPV±/EBV±/MMTV-like virus± (%)	p value
Age
≤50 years	3 (4)	22 (30)
>50 years	7 (9)	42 (57)	0.93
Total	10 (13)	64 (87)
Nottingham histological grade
Grade
I	4 (5.5)	10 (14)
II	4 (5.5)	36 (50)	0.25
III	2 (3)	16 (22)
Total	10 (14)	62 (86)
Tumor stage
Stage
Early stage (I–II)	6 (13)	33 (70)
Advanced stage (III–IV)	0 (0)	8 (17)	0.12
Total	6 (13)	41 (87)
ER status
ER+	8 (11)	51 (71)
ER–	2 (3)	11 (15)	0.79
Total	10 (14)	62 (86)
PR status
PR+	7 (10)	47 (65)
PR–	3 (4)	15 (21)	0.7
Total	10 (14)	62 (86)
HER-2 status
HER-2+	4 (6)	12 (17)
HER-2–	6 (8)	50 (69)	0.21
Total	10 (14)	62 (86)

HPV+/EBV+/MMTV-like virus + denotes a co-presence of HPV, EBV, and MMTV-like virus. HPV±/EBV±/MMTV-like virus±indicates a combination of HPV+/EBV–/MMTV-like virus– (HPV presence/EBV absence/MMTV-like virus absence), HPV–/EBV+/MMTV-like virus– (HPV absence/EBV presence/MMTV-like virus absence), HPV–/EBV–/MMTV-like virus+ (HPV absence/EBV absence/MMTV-like virus presence), and HPV–/EBV–MMTV– (lack of all the three HPV, EBV, and MMTV-like virus). * Indicates significant p values (<0.05).