Fig. 4.

PVAT anticontractile effect is absent in gracilis arteries from Adipo^−/− mice. Gracilis arteries from Adipo^−/− mice with and without PVAT were subjected to EFS, before incubating with CL-316,243 for 30 min and repeating the stimulus. Data shown are mean ± SEM (n = 8, p > 0.05 all comparisons). PVAT versus. +PVAT vessels were tested using two-way ANOVA. Before and after drugs within the same vessel type, e.g., −PVAT before drug versus. −PVAT after drug were tested using repeated-measures ANOVA. Both followed by Bonferroni post hoc tests.