Table 3.
Top 10 over-represented biological processes of down-regulated genes. The genes contributed to enrichment of each biological process are specified by italic characters
| Enriched biological processes and their associated genes | Enrichment ratio | P value |
|---|---|---|
|
Glucosylceramide metabolic process FA2H, UGCG |
60.2 | 0.000403 |
|
Response to platelet aggregation inhibitor GNAI1, FDX1 |
40.133 | 0.000997 |
|
Fatty acid metabolic process ACSL1, SLC27A6, PLA2G15, FA2H, FASN, PDK1, CPT1A, HACD2, ACOX1 |
6.7304 | 6.29E-06 |
|
Monocarboxylic acid metabolic process CYP1A2, ACSL1, SLC27A6, ATP8B1, PLA2G15, FA2H, FASN, PDK1, CPT1A, HACD2, ACOX1 |
5.1734 | 6.92E-06 |
|
Oxoacid metabolic process CYP1A2, GLCE, ACSL1, SLC27A6, ATP8B1, OAT, PLA2G15, AASS, FA2H, BCAT1, FASN, PDK1, CPT1A, HACD2, ACOX1 |
3.6857 | 8.1E-06 |
|
Organic acid metabolic process CYP1A2, GLCE, ACSL1, SLC27A6, ATP8B1, OAT, PLA2G15, AASS, FA2H, BCAT1, FASN, PDK1, CPT1A, HACD2, ACOX1 |
3.612 | 1.03E-05 |
|
Carboxylic acid metabolic process CYP1A2, ACSL1, SLC27A6, ATP8B1, OAT, PLA2G15, AASS, FA2H, BCAT1, FASN, PDK1, CPT1A, HACD2, ACOX1 |
3.6017 | 2.23E-05 |
|
Cellular lipid metabolic process CYP1A2, ACSL1, SLC27A6, PLA2G15, FA2H, FASN, UGCG, PDK1, PLD1, CPT1A, HACD2, ACOX1 |
3.1965 | 0.000291 |
|
Lipid metabolic process CYP1A2, ACSL1, SLC27A6, ATP8B1, PLA2G15, FDX1, FA2H, FASN, UGCG, PDK1, PLD1, CPT1A, HACD2, ACOX1 |
2.8473 | 0.000283 |
|
Small molecule metabolic process CYP1A2, GLCE, AHCYL2, ACSL1, SLC27A6, ATP8B1, OAT, PLA2G15, ACPP, FDX1, AASS, FA2H, BCAT1, FASN, PDK1, PDXK, CPT1A, EPM2AIP1, HACD2, ACOX1 |
2.5536 | 4.69E-05 |
Biological processes with FDR< 0.05 are shown by bold characters