Figure 7.

CircPLOD2 promoted tumor progression through the miR-513a-5p/SIX1 axis in vivo. (A) Representative images of tumors of HCT-116 cells with different transfection. (B and C) The tumor volume and weight were measured. (D) Representative images of H&E staining and IHC assay for Ki-67 expression in the tumor tissues. (E) The expression level of miR-513a-5p in tumor tissues was detected by qRT-PCR. (F) Representative blots and analyses for SIX1 and LDHA in circPLOD2-depleted tumor samples with or without miR-513a-5p inhibitor transfection. N = 3, all data were represented as mean ± SD. **p < 0.01, ***p < 0.001 vs. the sh-nc group.