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. 2022 Nov 18;14(1):2145843. doi: 10.1080/19490976.2022.2145843

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — The abundance of L. johnsonii was positively correlated with MRC1, IL10 and TLR1/2 in UC patients.

a, Schematic diagram showing that tissue samples from 13 patients with ulcerative colitis and 22 normal people were collected. b, Bacteria genomic DNA was extracted from colon tissues of UC patients and healthy people. The abundance of L. johnsonii was tested by RT-qPCR. c, The mRNA expression level of MRC1 were evaluated in UC patients and healthy people. d, The correlation of L. johnsonii and IL10 were analyzed. e, The correlation of L. johnsonii and MRC1 were analyzed. f, The correlation of L. johnsonii and TLR2 were analyzed. g, The correlation of L. johnsonii and TLR1 were analyzed. h, The correlation of MRC1 and IL10 were analyzed. i, The correlation of MRC1 and TLR2 were analyzed. j, The correlation of MRC1 and TLR1 were analyzed. k, The correlation of IL10 and TLR2 were analyzed. i, The correlation of TLR1 and IL10 were analyzed. Data are presented as mean ± SD, n = 13–22. *, P < .05; **, P < .01. Mann Whitney test (a-b), Spearman correlation analysis (d-l).