Table 1.

Comparison of clinical parameters between hemodialysis patients and normal controls.

Characteristics	Hemodialysis patients (n = 184)	Normal controls (n = 39)	t/κ2/Z value	p Value
Age (years)	60.1 ± 14.8	44.8 ± 12.6	6.002	<0.001
Gender (male, n, %)	123,66.8	15,38.5	10.993	0.001
Dialysis vintage (months)	56.0 (32.6–105.4)
Hemoglobin (g/L)	108.2 ± 11.6	144.0 ± 15.1	–13.930	<0.001
Albumin (g/L)	40.6 ± 3.4	44.8 ± 2.4	–7.115	<0.001
usCRP (mg/L)	2.81 (0.87,6.61)	0.72 (0.17–2.11)	–3.515	<0.001
Serum urea (mmol/L)	26.1 ± 5.6	4.7 ± 1.2	46.911	<0.001
Serum creatinine (µmol/L)	957.9 ± 269.3	72.9 ± 12.1	44.369	<0.001
Serum TMAO (µg/mL)	5.80 (3.96, 9.46)	0.18 (0.11, 0.32)	–9.782	<0.001
Ln(TMAO)	1.82 ± 0.62	–1.60 ± 0.77	29.835	<0.001

usCRP: ultrasensitive C-reactive protein; Ln(TMAO): the natural logarithm of trimethylamine-N-oxide.