Table 4.
Comparison of serum Ln(TMAO) and other parameters between the high AAC score group and the low AAC score group.
Characteristics | AAC score < 5.5 (n = 67) | AAC score ≥ 5.5 (n = 57) | p Value |
---|---|---|---|
Age (years) | 53.3 ± 14.2 | 66.0 ± 11.3 | <0.001 |
Gender, male, n (%) | 44 (65.7) | 35 (61.4) | 0.622 |
Dialysis vintage (months) | 53.9 (22.4, 74.3) | 75.2 (50.7, 142.1) | <0.001 |
Diabetes mellitus, n (%) | 19 (28.4) | 27 (47.4) | 0.029 |
Hemoglobin (g/L) | 108.6 ± 9.9 | 109.3 ± 11.8 | 0.722 |
Serum creatinine (µmol/L) | 1044.9 ± 311.8 | 897.5 ± 193.9 | 0.002 |
Kt/V urea (per week) | 1.28 ± 0.25 | 1.34 ± 0.17 | 0.125 |
Serum albumin (g/L) | 41.1 ± 3.3 | 40.5 ± 2.9 | 0.351 |
Serum corrected calcium (mmol/L) | 2.26 ± 0.18 | 2.28 ± 0.21 | 0.655 |
Serum phosphate (mmol/L) | 1.80 ± 0.52 | 1.77 ± 0.48 | 0.776 |
Serum usCRP (mg/L) | 2.07 (0.58, 6.56) | 3.39 (1.37, 8.12) | 0.076 |
Plasma iPTH (pg/mL) | 229.1(112.5, 443.5) | 368.0(212.2, 600.1) | 0.005 |
Serum CO2CP (mmol/L) | 19.7 ± 3.0 | 19.6 ± 2.2 | 0.844 |
Serum LDL-C (mmol/L) | 2.02 ± 0.63 | 1.96 ± 0.67 | 0.596 |
Serum HDL-C (mmol/L) | 1.00 ± 0.34 | 0.96 ± 0.35 | 0.530 |
Serum triglycerides (mmol/L) | 1.64 (0.92, 2.50) | 1.98 (1.18, 2.89) | 0.123 |
Serum Ln(TMAO) | 1.67 ± 0.54 | 2.09 ± 0.55 | <0.001 |
AAC (score) | 2 (0, 3) | 9 (6.5, 13) | <0.001 |
Ln(TMAO): the natural logarithm of trimethylamine-N-oxide; AAC: abdominal aortic calcification; Kt/V urea: fractional urea clearance; usCRP: ultrasensitive C-reactive protein; iPTH: intact parathyroid hormone; CO2CP: carbon dioxide combining power; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol.