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. 2022 Nov 16;44(1):2019–2027. doi: 10.1080/0886022X.2022.2145971

Table 4.

Comparison of serum Ln(TMAO) and other parameters between the high AAC score group and the low AAC score group.

Characteristics AAC score < 5.5 (n = 67) AAC score ≥ 5.5 (n = 57) p Value
Age (years) 53.3 ± 14.2 66.0 ± 11.3 <0.001
Gender, male, n (%) 44 (65.7) 35 (61.4) 0.622
Dialysis vintage (months) 53.9 (22.4, 74.3) 75.2 (50.7, 142.1) <0.001
Diabetes mellitus, n (%) 19 (28.4) 27 (47.4) 0.029
Hemoglobin (g/L) 108.6 ± 9.9 109.3 ± 11.8 0.722
Serum creatinine (µmol/L) 1044.9 ± 311.8 897.5 ± 193.9 0.002
Kt/V urea (per week) 1.28 ± 0.25 1.34 ± 0.17 0.125
Serum albumin (g/L) 41.1 ± 3.3 40.5 ± 2.9 0.351
Serum corrected calcium (mmol/L) 2.26 ± 0.18 2.28 ± 0.21 0.655
Serum phosphate (mmol/L) 1.80 ± 0.52 1.77 ± 0.48 0.776
Serum usCRP (mg/L) 2.07 (0.58, 6.56) 3.39 (1.37, 8.12) 0.076
Plasma iPTH (pg/mL) 229.1(112.5, 443.5) 368.0(212.2, 600.1) 0.005
Serum CO2CP (mmol/L) 19.7 ± 3.0 19.6 ± 2.2 0.844
Serum LDL-C (mmol/L) 2.02 ± 0.63 1.96 ± 0.67 0.596
Serum HDL-C (mmol/L) 1.00 ± 0.34 0.96 ± 0.35 0.530
Serum triglycerides (mmol/L) 1.64 (0.92, 2.50) 1.98 (1.18, 2.89) 0.123
Serum Ln(TMAO) 1.67 ± 0.54 2.09 ± 0.55 <0.001
AAC (score) 2 (0, 3) 9 (6.5, 13) <0.001

Ln(TMAO): the natural logarithm of trimethylamine-N-oxide; AAC: abdominal aortic calcification; Kt/V urea: fractional urea clearance; usCRP: ultrasensitive C-reactive protein; iPTH: intact parathyroid hormone; CO2CP: carbon dioxide combining power; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol.