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. 2022 Nov 7;14:993621. doi: 10.3389/fnagi.2022.993621

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Copyright © 2022 Criscuolo, Cennamo, Montorio, Carotenuto, Migliaccio, Moccia, Salvatore, Lanzillo, Costagliola and Morra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Left eye of a patient affected by MCI (72 years-old male) shows at structural spectral domain- optical coherence tomography (SD-OCT) an increased reduction in ganglion cell complex (GCC) (A1) and in retinal nerve fiber layer (RNFL) (B1) respect to baseline (A,B). OCT Angiography images reveals a relevant vessel density reduction for superficial capillary plexus (SCP) (C1), deep capillary plexus (DCP) (D1), and radial peripapillary capillary plexus (RPC) (F1) at year 1 respect to baseline (C,D,F). Vessel density in the choriocapillaris (CC) does not change over the follow-up (E,E1). The Foveal Avascular Zone (FAZ) area reveals an increased size at follow up (G1) respect to baseline (G).