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. 2022 Nov 7;14:993621. doi: 10.3389/fnagi.2022.993621

Table 3.

Comparison in SD-OCT and OCTA parameters among non-converters vs. converters at baseline vs. follow-up.

Baseline Follow-up Non-converters follow-up vs. baseline Converters follow-up vs. baseline
Non-converters Converters Non-converters Converters EMD P-value EMD P-value
SD-OCT (μM)
GCC average 92.7 ± 11 91.5 ± 6.4 88.8 ± 11 86.7 ± 6.4 −3.8 0.04 −4.79 <0.001
RNFL average 95.6 ± 9.4 96.6 ± 7.1 92.3 ± 9.3 91.9 ± 7 −4.3 <0.001 −4.71 <0.001
OCTA (%)
SCP whole 45.7 ± 4.9 44.6 ± 4.1 42.6 ± 4.9 41.7 ± 4.2 −3.19 0.001 −2.93 0.005
DCP whole 46.6 ± 5.3 43.6 ± 7.4 42.6 ± 4.4 41.4 ± 7.4 −4.2 <0.001 −2.22 0.26
CC whole 69.8 ± 3.9 70.6 ± 5.3 69.5 ± 4.5 70.4 ± 5.5 −0.3 0.6 −0.20 0.72
RPC whole 46.4 ± 4.8 46.7 ± 5.7 43.2 ± 5.1 42.3 ± 5.8 −3.22 <0.001 −4.40 <0.001
FAZ area 0.3 ± 0.1 0.3 ± 0.2 0.4 ± 0.1 0.4 ± 0.1 0.12 <0.001 0.01 0.005

SD-OCT, spectral domain optical coherence tomography; EMD, estimated mean difference; GCC, ganglion cell complex; RNFL, retinal nerve fiber layer; OCTA, OCT angiography; SCP, superficial capillary plexus; DCP, deep capillary plexus; CC, choriocapillary plexus; RPC, radial peripapillary capillary; FAZ, foveal avascular zone.

Linear mixed models, P value < 0.05.