Table 3.
Detailed table of differential metabolites in meropenem-free and subinhibitory concentrations of meropenem.
| No. | Metabolite | M/Zc | Mode | Formula | Retention time | Log2FC (SW1786/SW1780) | P_value | Variatio trend (SW1786/SW1780) |
|---|---|---|---|---|---|---|---|---|
| 1 | 7,8-dimethylalloxazine | 523.1237 | Posa | C12H10N4O2 | 4.1390 | −0.788 | 0.004556 | ↓ |
| 2 | Phenylalanylproline | 245.1280 | Pos | C14H18N2O3 | 3.8740 | 1.2814 | 0.001219 | ↑ |
| 3 | B-D-fructosyl-a-D-(6-O-(E))-feruloylglucoside | 437.1485 | Pos | C21H28O12 | 3.6116 | 0.7985 | 0.00295 | ↓ |
| 4 | Pterosin J | 235.0862 | Pos | C14H17ClO2 | 3.8935 | 1.2153 | 0.001045 | ↑ |
| 5 | PS (16:0/16:0) | 756.4870 | Negb | C38H74NO10P | 11.2093 | 1.5517 | 0.04325 | ↑ |
| 6 | Endomorphin-1 | 631.2632 | Neg | C34H38N6O5 | 8.6796 | 1.3323 | 0.002773 | ↑ |
| 7 | Hawkinsin | 312.0505 | Neg | C11H17NO6S | 1.4909 | 1.2577 | 0.02385 | ↑ |
| 8 | L-phenylalanyl-L-hydroxyproline | 313.0940 | Neg | C14H18N2O4 | 3.694 | 0.8231 | 0.01152 | ↓ |
| 9 | Corchoionoside B | 445.1719 | Neg | C19H28O9 | 1.2181 | 1.2188 | 0.0148 | ↑ |
a
Positive ion.
b
Negative ion.
c
Mass-to-charge ratio.