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Connectivity and mutation rate of core mutated genes in the PPI network
| Genes | Degree | Mutation rate |
|---|---|---|
| TP53 | 64 | 47.9% |
| ATM | 58 | 3.2% |
| PTEN | 57 | 2.1% |
| BRCA1 | 56 | 2.4% |
| HRAS | 55 | 0.6% |
| KRAS | 55 | 7.4% |
| PIK3CA | 55 | 4.1% |
| MYC | 54 | 0.3% |
| CDKN2A | 52 | 4.7% |
| CTNNB1 | 51 | 8.5% |
| MDM2 | 51 | 1.1% |
| EGFR | 50 | 63.5% |
| ERBB2 | 50 | 2.4% |
