FIG. 7.

Change in DTH response (footpad swelling) and serum immune response to H. pylori antigens in infected and uninfected recipient SCID mice. (A) Infected SCID recipients of splenocytes from infected donors developed strong DTH responses by 2 weeks posttransfer (PT). Serum IgG responses developed later and remained consistently lower than those in C57BL/6 mice. Responses of SCID recipients of splenocytes from uninfected donors were similar (not shown). ∗, P < 0.05 compared to results for nonrecipients. (B) DTH and serum immune responses were low and inconsistent in uninfected SCID recipients of splenocytes from infected donors. OD₄₀₅, optical density at 405 nm.