TABLE 2.
Bacterial colonization and epithelial changes in mice killed 3 months after adoptive transfera
| Group | n | % Mucosa with:
|
Labeling index | H. pylori in gastric mucosa (106 CFU/g) | |||
|---|---|---|---|---|---|---|---|
| Gastritis | Mucus metaplasia | Intestinal metaplasia | Erosions | ||||
| Uninfected C57BL/6 | 5 | 0.8 ± 0.8* | 0 | 16.0 ± 2.2 | 0 | 38.6 ± 3.0 | 0 |
| Infected C57BL/6 | 6 | 46.3 ± 6.3 | 6.2 ± 2.8 | 28.7 ± 7.9 | 0 | 46.0 ± 0.0 | 11.6 ± 2.7 |
| Uninfected SCID | 5 | 13.0 ± 3.1* | 0 | 15.2 ± 5.9 | 0 | 40.0 ± 1.7 | 0 |
| Infected SCID | 5 | 0.6 ± 0.6* | 0 | 3.2 ± 2.5 | 0 | 41.6 ± 1.0 | 60.1 ± 3.8* |
| Infected recipient SCID, infected donor | 6 | 69.0 ± 3.8* | 24.3 ± 5.9* | 52.3 ± 11.4 | 3.5 ± 1.6 | 45.8 ± 2.9 | 0.2 ± 0.01* |
| Infected recipient SCID, uninfected donor | 5 | 97.8 ± 2.2* | 94.4 ± 5.6* | 84.6 ± 1.03* | 10.6 ± 6.7 | 52.5 ± 6.0 | 0.1 ± 0.01* |
a
Values are means ± standard deviations. *, significantly different from infected C57BL/6 mice (P < 0.05).