The National Institute for Health and Care Excellence 2021 guidelines on chronic kidney disease (CKD) recommended GPs use the Kidney Failure Risk Equation (KFRE) to guide referrals to nephrology. The equation used for estimating glomerular filtration rate (eGFR) has been updated. In a Welsh primary care population (Secure Anonymised Information Linkage Databank), there was a 1.2-fold fall in new CKD diagnoses if laboratories used the updated equation to report eGFR. New CKD referral criteria identify patients at high risk of CKD progression before their eGFR falls below 30 mL/min/1.73 m2, particularly among minority ethnic groups. Implementation of KFRE will rely on raising awareness among GPs and improved albuminuria testing rates, which are currently low. |